Mental health
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- today x.com
Semax reduced amyloid plaques in Alzheimer's model mice
In mice used as an Alzheimer's model, one month of nasal Semax reduced amyloid plaques in the cortex by 2.8 times and improved cognitive tests. The results are preliminary and show no direct effect in people.
- 11 days ago x.com
Lower testosterone linked to cognitive decline in 581 men
A study of 581 men followed for 7 years found an inverse link between total and free testosterone and cognitive decline. The association does not prove cause.
- 14 days ago x.com
Study: heavy alcohol makes brain immune cells break down neural scaffold
Researchers at the Cleveland Clinic report that intense alcohol exposure caused brain microglia to retract their branches and remove the extracellular matrix within one hour, pointing to a possible mechanism behind alcohol-related brain changes.
- 19 days ago x.com
Daytime naps linked with larger brain volume in a large study
A study of about 400,000 people linked daytime napping with greater total brain volume. The result is observational and does not prove that napping causes this effect.
- 19 days ago academic.oup.com
Brain energy metabolism and cognitive impairment in psychosis
A new report describes an association between impaired brain energy metabolism and cognitive impairment in psychotic disorders, a link that future research is expected to explore.
- 19 days ago psypost.org
Better diets linked to sharper focus in teens with attention disorders
A small study links a Mediterranean-style diet and certain vitamins to better performance on attention tests in teens with attention disorders.
- 19 days ago psypost.org
Brain white matter linked to how trauma memories intrude
A PsyPost report describes a study linking the microscopic integrity of white matter in specific brain pathways to how traumatic flashbacks are experienced.
- 19 days ago nature.com
AI-enhanced MRI reveals cortical lesions in multiple sclerosis
A study reanalysed standard MRI scans from a large multiple sclerosis clinical trial using multicontrast processing and deep learning, improving detection of cortical lesions.
- 19 days ago journals.plos.org
Brain wave bands separate causal and contextual signals in visual decisions
A research article reports that high-gamma activity in the visual cortex reflects causal contributions to perceptual decisions, while lower frequency bands indicate contextual influences.
- 19 days ago psypost.org
Brainstem circuit linked to long-lasting anxiety in mice
A PsyPost report on a mouse study linked activating a brainstem circuit to long-lasting anxiety. Temporarily switching it off blocked effects of intense stress. These are animal research results, still far from application in people.
- 19 days ago thelancet.com
Chronic poor sleep linked to inflammation and faster brain aging
A study published in EBioMedicine, a journal in The Lancet family, linked chronic poor sleep quality to higher inflammation and a larger brain age gap, a sign of accelerated brain aging.
- 19 days ago nature.com
Less visceral fat over time linked to slower brain shrinkage in midlife
A study in Nature Communications of 533 adults, average age 61, linked sustained loss of visceral fat to less brain atrophy and better cognition, mainly through blood sugar control.
- 19 days ago sciencedirect.com
Navitoclax nanoparticles reduce aged cells in the brain barrier of rats
In naturally aged rats, nanoparticles releasing navitoclax reduced senescent cells lining the blood-brain barrier and decreased barrier leakage. This is early preclinical research in animals, with no cognitive gains reported.
- 19 days ago frontiersin.org
Neuroinflammation and treatment resistance in depression
An article in Frontiers in Pharmacology describes major depression as a multi-system disease and focuses on the link between inflammation and depression that does not respond to standard treatment.
- 19 days ago nature.com
Systematic review of ketogenic interventions in serious mental illness
A systematic review and meta-analysis of 73 studies examines ketogenic diet interventions and their effects on neuropsychological and metabolic outcomes in serious mental illness and neurocognitive disorders.
- 19 days ago x.com
Chronic inflammation may shift brain repair cells away from making neurons
A study published in Nature Communications found that chronic TNF-α pushed human hippocampal progenitor cells into an interferon-driven immune alert state, suppressing neurogenesis. The evidence comes from cell models, not people.
- 19 days ago x.com
Ergothioneine may strengthen circadian rhythm in rodents
A study in rodents suggests that ergothioneine may increase circadian robustness and counter NAD+ depletion. The results come from research in animals.
- 19 days ago x.com
Fecal transplants from depressed patients induce depression-like traits in rats
In a rat study, fecal transplants from 34 people with depression produced reduced sucrose preference, anxiety-like behavior and altered tryptophan metabolism.
- 19 days ago x.com
LSD-derived compound improved mood and cognition in mice
In a study of mice, JRT, a modified version of the LSD molecule, improved behaviors linked to cognition and mood without psychosis-like symptoms. This early animal research is not yet a treatment.
- 19 days ago x.com
Mental health improved with age in a study of 1,546 adults
A study of 1,546 adults aged 21 to 100 reported that physical health and cognitive function declined over adult life, while mental health improved. The findings suggest these areas can follow different paths.
- 19 days ago x.com
Night-time low blood sugar can disrupt sleep in healthy adults
A study of healthy people linked drops in blood sugar during the night to lighter sleep and early waking.
- 19 days ago x.com
Probiotics versus placebo in major depression: results of an 8-week trial
A randomized clinical trial lasting 8 weeks compared probiotics with placebo in people with major depression. The trial reported improved depressive symptoms and some metabolic markers.
- 19 days ago x.com
Red light improved memory in mice, an animal study
A mouse study reported that red light reduced oxidative stress and restored memory. It is early research, and results in animals do not yet show a treatment for people.
- 19 days ago x.com
Removing FTL1 protein restored synapses and memory in aging mice
A UCSF study in mice linked the FTL1 protein to synapse loss and memory decline. In older mice, removing it restored synapses and memory.
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