Supplements
Supplements, peptides and nutrition: what was tested, in whom, and how strong the evidence is.
- SupplementsArticle
Review of taurine supplementation, metabolism, inflammation and aging
A review article examines taurine supplementation from mechanistic and nutritional perspectives, linking it to metabolism, inflammation and aging.
- SupplementsPost
Meta-analysis of cerebrolysin trials in mild-to-moderate Alzheimer's
A meta-analysis of six clinical trials involving 784 people with mild-to-moderate Alzheimer's found benefits on several cognitive measures, but the findings call for caution.
- SupplementsArticle
Caffeine and heart disease: what the AHA statement reviews
The American Heart Association has published a scientific statement reviewing evidence on caffeine and heart disease. According to the passage, studies associated moderate coffee intake with a lower risk of stroke.
- SupplementsArticle
Garlic and its metabolites in degenerative musculoskeletal disease
An article in Frontiers in Pharmacology covers garlic and its active metabolites in osteoarthritis, osteoporosis and disc degeneration, conditions that become more common with age.
- SupplementsArticle
Menadione slows prostate cancer in mice in early animal study
A study in mice reports that menadione, a precursor of vitamin K, slowed prostate cancer by interfering with the survival processes of cancer cells. The results come from animal research, not trials in people.
- SupplementsArticle
Peptide vaccine targeting PCSK9 lowers cholesterol and plaque in mice
A study in mice reported that a peptide vaccine targeting PCSK9 reduced cholesterol and atherosclerotic plaque. The evidence comes from animal experiments, not from people.
- SupplementsArticle
Urolithin A and age-related hearing loss in mice
A study in mice reports that urolithin A prevented age-related hearing loss, probably through mitophagy. The results come from animals and do not show whether the effect occurs in people.
- SupplementsPost
Peptide GUB-UCN2 raised lean mass and cut fat in obese rats
In a 12-week study of obese rats, the peptide GUB-UCN2 alone increased lean mass and reduced fat. According to the author, human trials have already begun.
- SupplementsPost
Peptron seeks to start Phase 1 trial of monthly semaglutide
The company Peptron has asked for approval to test PT403, a monthly semaglutide formulation, in people. The early data come from a small study, disclosed by the company itself and not yet peer reviewed.
- SupplementsPost
Study reports berberine lowered fasting glucose and raised GLP-1
A reported study of people who took a specific form of berberine for two weeks found lower fasting glucose, better glucose tolerance and higher levels of the hormone GLP-1.
- SupplementsPost
Urolithin A reversed heart failure in mice via two pathways
In mice, urolithin A reversed heart failure through mitophagy in heart cells and through changes in gut bacteria that produce toxic ceramides. The results come only from animals.
- SupplementsPost
Vitamin C partially reverses bone marrow aging in primates
A study in non-human primates used single-cell analysis to map aging in bone marrow. Prolonged oral vitamin C partly reversed age-related changes and reduced estimated biological age by about four years.
- SupplementsPost
Preliminary study: NAC limited weight gain on a fattening diet
According to the report, NAC reduced body weight and liver fat and improved insulin sensitivity in a study using a diet that favors weight gain, without changing calorie intake.
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