Roadmap lists 100 open problems in ageing science
A review gathers 100 unresolved questions about ageing and longevity, compiled with the research community and analyzed with natural language processing to find gaps in research.
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What the research shows
The review presents a curated list of 100 open questions in research on ageing and longevity. According to the article, the list was assembled with the research community and analyzed with natural language processing, a computing technique that examines large volumes of text, to identify gaps in current knowledge. The goal is to show what remains unresolved in this field.
Open questions are a normal part of scientific work: a list like this offers no answers, but it points to where evidence is missing. It can guide future studies on health across the lifespan. As an overview of questions, the review does not test interventions or draw clinical conclusions.
What it means
The list shows where ageing science still needs answers, which can help guide future research. It is not yet known which of these questions will be resolved first or which will have the greatest impact on health. It is a map of questions, not of discoveries.
How to read it with care
A list of open problems neither proves nor rules out any hypothesis about ageing. It does not replace a medical consultation: anyone considering changes to diet, supplements or treatment should talk to a doctor or another qualified health professional.