Enzyme reverses protein chemical aging in lab and tissue samples
A Nature Communications study describes the enzyme CMLase, which acts on a glycation marker and restores proteins in laboratory tests and in human tissue samples.
Source: Enzyme reverses protein chemical aging in lab and tissue samples (nature.com). Summary written with AI from the source and reviewed by rules; read the original.
What the research shows
The study, published in Nature Communications, reports that the enzyme CMLase oxidizes the glycation marker called CML and restores native lysine residues in in vitro experiments (in test tubes) and in human tissue samples. No trials in people were conducted: the results come from laboratory and tissue work.
Glycation is a chemical reaction in which sugars attach to proteins, and the buildup of this damage is studied as part of aging. This is early research on a possible mechanism, with no proven benefits in people. A finding in cells and tissues is still far from a safe application for health.
What it means
The finding suggests that one type of chemical damage to proteins may, in principle, be reversed in the laboratory. It is not yet known whether this happens in a living human body, whether it is safe, or whether it changes health or lifespan.
How to read it with care
This result does not replace a medical consultation. Anyone considering a change in diet, supplements or treatment should talk to a doctor or another qualified professional.