Aging · 5
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Pilot mouse study reports protection against frailty and longer life
A pilot study in rapidly aging mice, presented at a congress, reports protection against frailty and a maximum lifespan extended by more than 33%. The results are preliminary and come from animals.
Preprint suggests epigenetic disorder rises with age in mammals
A preprint asks whether the epigenome becomes more disordered with aging. According to the publication, the answer appears to be yes in mammals, but the study has not yet undergone peer review.
Seven proposed hallmarks of muscle health, with regeneration among them
A review in Nature Metabolism, written by muscle biologists, proposes seven interconnected hallmarks of muscle health. The third is regenerative capacity, supported by satellite stem cells.
SIRT6 and longevity: what a social media post claims and what still needs proof
A social media post presents the protein SIRT6 as a key to longevity. The post cites no study, so its claims need checking against primary research.
Lipid chain length may drive cell aging, authors say
An article describes a study linking longer lipid chains in cell membranes with age and a drop in cell viability, and notes that certain interventions reversed this trend in the study.
Grape-seed compound PCC1 tested against aging cells in early mouse studies
Early mouse studies in China suggest that PCC1, a grape-seed compound, may extend life by acting on damaged cells. There are not yet human studies confirming this.
Mitochondrial transplant restores heart cleanup in aged mice
A mouse study in Aging Cell reports that transplanted healthy mitochondria restored mitophagy, the process that removes damaged mitochondria, in aging hearts.
Redesigned fisetin version shows greater potency in mouse cells
Researchers at the University of Minnesota redesigned fisetin, a plant compound. In aging mouse cells, the new version was described by the author as 27 times more potent. The result comes from laboratory work, not from studies in people.
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