Mental health
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- today x.com
Semax reduced amyloid plaques in Alzheimer's model mice
In mice used as an Alzheimer's model, one month of nasal Semax reduced amyloid plaques in the cortex by 2.8 times and improved cognitive tests. The results are preliminary and show no direct effect in people.
- 11 days ago x.com
Lower testosterone linked to cognitive decline in 581 men
A study of 581 men followed for 7 years found an inverse link between total and free testosterone and cognitive decline. The association does not prove cause.
- 14 days ago x.com
Study: heavy alcohol makes brain immune cells break down neural scaffold
Researchers at the Cleveland Clinic report that intense alcohol exposure caused brain microglia to retract their branches and remove the extracellular matrix within one hour, pointing to a possible mechanism behind alcohol-related brain changes.
- 19 days ago x.com
Daytime naps linked with larger brain volume in a large study
A study of about 400,000 people linked daytime napping with greater total brain volume. The result is observational and does not prove that napping causes this effect.
- 19 days ago x.com
Chronic inflammation may shift brain repair cells away from making neurons
A study published in Nature Communications found that chronic TNF-α pushed human hippocampal progenitor cells into an interferon-driven immune alert state, suppressing neurogenesis. The evidence comes from cell models, not people.
- 19 days ago x.com
Ergothioneine may strengthen circadian rhythm in rodents
A study in rodents suggests that ergothioneine may increase circadian robustness and counter NAD+ depletion. The results come from research in animals.
- 19 days ago x.com
Fecal transplants from depressed patients induce depression-like traits in rats
In a rat study, fecal transplants from 34 people with depression produced reduced sucrose preference, anxiety-like behavior and altered tryptophan metabolism.
- 19 days ago x.com
LSD-derived compound improved mood and cognition in mice
In a study of mice, JRT, a modified version of the LSD molecule, improved behaviors linked to cognition and mood without psychosis-like symptoms. This early animal research is not yet a treatment.
- 19 days ago x.com
Mental health improved with age in a study of 1,546 adults
A study of 1,546 adults aged 21 to 100 reported that physical health and cognitive function declined over adult life, while mental health improved. The findings suggest these areas can follow different paths.
- 19 days ago x.com
Night-time low blood sugar can disrupt sleep in healthy adults
A study of healthy people linked drops in blood sugar during the night to lighter sleep and early waking.
- 19 days ago x.com
Probiotics versus placebo in major depression: results of an 8-week trial
A randomized clinical trial lasting 8 weeks compared probiotics with placebo in people with major depression. The trial reported improved depressive symptoms and some metabolic markers.
- 19 days ago x.com
Red light improved memory in mice, an animal study
A mouse study reported that red light reduced oxidative stress and restored memory. It is early research, and results in animals do not yet show a treatment for people.
- 19 days ago x.com
Removing FTL1 protein restored synapses and memory in aging mice
A UCSF study in mice linked the FTL1 protein to synapse loss and memory decline. In older mice, removing it restored synapses and memory.
- 19 days ago x.com
Single creatine dose linked to brain changes in sleep-deprived adults
A Scientific Reports study of 15 healthy people kept awake for 21 hours found that a single creatine dose improved cognitive performance and changed brain energy metabolism within hours, under specific metabolic conditions.
- 19 days ago x.com
Bowel evacuation linked to faster Stroop times in elite triathletes
A randomized crossover trial in elite triathletes found faster Stroop test response times after bowel evacuation. Near-infrared measurements of the prefrontal cortex showed no relevant change.
- 19 days ago x.com
L-theanine trial links lower stress and cortisol in people
A double-blind, placebo-controlled, crossover trial in people found that an L-theanine drink reduced self-reported stress and cortisol during a cognitive stressor. Alpha brain activity rose only in people with higher anxiety.
- 19 days ago x.com
Review links physical activity to brain waste clearance with aging
A review published in Trends in Neurosciences looks at how physical activity may regulate the glymphatic system, which helps clear proteins linked to Alzheimer's, such as beta-amyloid and tau.
- 19 days ago x.com
Saffron and antidepressants show similar results in small studies
A 2025 meta-analysis pooled eight studies with people and found no significant difference between saffron and SSRI antidepressants for mild to moderate depression.
- 19 days ago x.com
Study in Neuron links tau protein and mitochondrial damage in Alzheimer's
A study led by Stanford and published in the journal Neuron describes a cycle in which tau protein damages mitochondria, and mitochondrial signals in turn worsen tau.
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